Longitudinal Brain Volume Measurement in Multiple Sclerosis
نویسندگان
چکیده
منابع مشابه
Impact of inflammation on brain volume in multiple sclerosis.
OBJECTIVE To study changes in brain volume measured monthly in patients treated for relapsing multiple sclerosis due to loss of tissue and the appearance of inflammation. DESIGN AND PATIENTS The results from T2/fluid-attenuated inversion recovery axial images from 13 consecutive monthly 3-T brain magnetic resonance imaging tests conducted on 74 patients diagnosed with relapsing multiple scler...
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The development of sophisticated magnetic resonance imaging techniques and software for medical imaging processing and analysis has led to a significant progress in multiple sclerosis research and clinical care. The measurement of brain volumes provides a quantitative representation of damage, thus facilitating the objective follow-up process. The parameters obtained, though not being used rout...
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Multiple sclerosis (MS) is a chronic disease with an inflammatory and neurodegenerative pathology. Axonal loss and neurodegeneration occurs early in the disease course and may lead to irreversible neurological impairment. Changes in brain volume, observed from the earliest stage of MS and proceeding throughout the disease course, may be an accurate measure of neurodegeneration and tissue damage...
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Neurodegenerative diseases are often associated with loss of brain tissue volume. Our objective was to develop and evaluate a fully automated method to estimate cerebral volume from magnetic resonance images (MRI) of patients with multiple sclerosis (MS). In this study, MRI data from 17 normal subjects and 68 untreated MS patients was used to test the method. Each MRI volume was corrected for i...
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BACKGROUND AND PURPOSE Brain volume loss is currently a MR imaging marker of neurodegeneration in MS. Available quantification algorithms perform either direct (segmentation-based techniques) or indirect (registration-based techniques) measurements. Because there is no reference standard technique, the assessment of their accuracy and reliability remains a difficult goal. Therefore, the purpose...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2002
ISSN: 0003-9942
DOI: 10.1001/archneur.59.10.1572